Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 10/20 | 0.52 |
| ▸ | THRB | P10828 | 10/20 | 0.52 |
| ▸ | RARB | P10826 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RARA | P10276 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12044522 | 0.82 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9668006 | 0.82 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9667123 | 0.82 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL19130413 | 0.82 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9667141 | 0.82 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL195471 | 0.82 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9667265 | 0.82 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9667335 | 0.82 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL2394801 | 0.81 | THRA (0.56) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL19115372 | 0.81 | THRA (0.56) | THRATHRBRARBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2702034-A2 | PREPARATION OF FINGOLIMOD AND ITS SALTS | Dr. Reddy's Laboratories Ltd. (IN) | 2014-03-05 | — | — | EP | disclosed |
| WO-2012146980-A2 | PREPARATION OF FINGOLIMOD AND ITS SALTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-11-01 | — | — | WO | disclosed |