Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 6/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 6/20 | 0.53 |
| ▸ | ATR | Q13535 | 12/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12092426 | 0.81 | CYP4F2 (0.52) | CYP4F2CYP4A11ATRHCRTR1HCRTR2 | |
| SCHEMBL30088736 | 0.81 | NR3C2 (0.46) | ALDH1A1 | |
| SCHEMBL19732434 | 0.80 | ATR (0.54) | CYP4F2CYP4A11ATRHCRTR1HCRTR2 | |
| SCHEMBL19277442 | 0.80 | CYP4F2 (0.64) | CYP4F2CYP4A11ATRHCRTR1HCRTR2 | |
| SCHEMBL30509486 | 0.80 | CYP4F2 (0.58) | CYP4F2CYP4A11ATR | |
| SCHEMBL18034742 | 0.80 | CYP4F2 (0.57) | CYP4F2CYP4A11ATRALDH1A1 | |
| SCHEMBL26986513 | 0.80 | CYP4F2 (0.48) | CYP4F2CYP4A11ATRHCRTR1HCRTR2 | |
| SCHEMBL9977805 | 0.80 | CYP4F2 (0.58) | CYP4F2CYP4A11ATR | |
| SCHEMBL16589766 | 0.79 | CYP4F2 (0.48) | CYP4F2CYP4A11ATRHCRTR1HCRTR2 | |
| SCHEMBL24409265 | 0.78 | CYP4F2 (0.58) | CYP4F2CYP4A11ATRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012145581-A1 | DISUBSTITUTED OCTAHY-DROPYRROLO [3,4-C] PYRROLES AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2012-10-26 | — | — | WO | disclosed |