SCHEMBL9977805

SCHEMBL9977805

Fc1ccc(-c2ccnn2C2CCCCO2)nc1

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 6/20 0.58
CYP4A11 Q02928 6/20 0.58
ATR Q13535 14/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30509486 1.00 CYP4F2 (0.58) CYP4F2CYP4A11ATR
SCHEMBL19277442 0.85 CYP4F2 (0.64) CYP4F2CYP4A11ATR
SCHEMBL18034742 0.85 CYP4F2 (0.57) CYP4F2CYP4A11ATR
SCHEMBL9977842 0.84 CYP4F2 (0.54) CYP4F2CYP4A11ATR
SCHEMBL24409265 0.82 CYP4F2 (0.58) CYP4F2CYP4A11ATR
SCHEMBL19276681 0.81 CYP4F2 (0.65) CYP4F2CYP4A11ATR
SCHEMBL13734367 0.80 CYP4F2 (0.53) CYP4F2CYP4A11ATR
SCHEMBL25257638 0.80 CYP4F2 (0.53) CYP4F2CYP4A11ATR
SCHEMBL19277056 0.80 CYP4F2 (0.68) CYP4F2CYP4A11ATR
SCHEMBL25325198 0.79 CYP4F2 (0.42) CYP4F2CYP4A11ATR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230339900-A1 CASEIN KINASE 1 DELTA MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2023-10-26 US disclosed
US-20230339900-A1 CASEIN KINASE 1 DELTA MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2023-10-26 US disclosed
US-20230339900-A1 CASEIN KINASE 1 DELTA MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2023-10-26 US disclosed
EP-4214199-A1 CASEIN KINASE 1 DELTA MODULATORS JANSSEN Pharmaceutica NV (BE) 2023-07-26 EP disclosed
CN-116490503-A Casein kinase 1 delta modulators 詹森药业有限公司 2023-07-25 CN disclosed
US-11198690-B2 Method for producing (2S)-2-[(1H-pyrazol-1-yl)methyl]-1,3-oxazinane derivative TAISHO PHARMACEUTICAL CO., LTD. (JP) 2021-12-14 US disclosed
US-20210147400-A1 METHOD FOR PRODUCING (2S)-2-[(1H-PYRAZOL-1-YL)METHYL]-1,3-OXAZINANE DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2021-05-20 US disclosed
EP-3653623-A1 METHOD FOR PRODUCING (2S)-2-[(1H-PYRAZOL-1-YL)METHYL]-1,3-OXAZINANE DERIVATIVE Taisho Pharmaceutical Co., Ltd. (JP) 2020-05-20 EP disclosed
WO-2019013244-A1 METHOD FOR PRODUCING (2S)-2-[(1H-PYRAZOL-1-YL)METHYL]-1,3-OXAZINANE DERIVATIVE 大正製薬株式会社 2019-01-17 WO disclosed
EP-2862860-B1 1,3-OXAZOLIDINE OR 1,3-OXAZINANE COMPOUNDS AS OREXIN RECEPTOR ANTAGONISTS TAISHO PHARMACEUTICAL CO LTD (JP) 2016-12-21 EP disclosed
US-20150166523-A1 BRANCHED CHAIN ALKYL HETEROAROMATIC RING DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2015-06-18 US disclosed
US-20150166523-A1 BRANCHED CHAIN ALKYL HETEROAROMATIC RING DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2015-06-18 US disclosed
EP-2862860-A1 HETEROAROMATIC METHYL CYCLIC AMINE DERIVATIVE Taisho Pharmaceutical Co., Ltd. (JP) 2015-04-22 EP disclosed
EP-2862855-A1 BRANCHED CHAIN ALKYL HETEROAROMATIC RING DERIVATIVE Taisho Pharmaceutical Co., Ltd. (JP) 2015-04-22 EP disclosed
WO-2013187466-A1 BRANCHED CHAIN ALKYL HETEROAROMATIC RING DERIVATIVE 大正製薬株式会社 (JP) 2013-12-19 WO disclosed
US-20130281465-A1 PYRAZOLE DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2013-10-24 US disclosed
US-20130281465-A1 PYRAZOLE DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2013-10-24 US disclosed
US-20130281465-A1 PYRAZOLE DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2013-10-24 US disclosed
EP-2653469-A1 PYRAZOLE DERIVATIVE Taisho Pharmaceutical Co., Ltd. (JP) 2013-10-23 EP disclosed
WO-2012081692-A1 PYRAZOLE DERIVATIVE 大正製薬株式会社 (JP) 2012-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150166523-A1 BRANCHED CHAIN ALKYL HETEROAROMATIC RING DERIVATIVE HCRTR2, HCRTR1, HTR2B CYP4F2 974/4885CYP4A11 467/4885ATR 4245/4885
US-20230339900-A1 CASEIN KINASE 1 DELTA MODULATORS CSNK1D, CSNK1A1, CSNK2A1 CYP4F2 3905/4885CYP4A11 2649/4885ATR 2354/4885
US-11198690-B2 Method for producing (2S)-2-[(1H-pyrazol-1-yl)methyl]-1,3-oxazinane derivative AGXT, GRHPR, HPD CYP4F2 317/4885CYP4A11 277/4885ATR 2179/4885
US-20130281465-A1 PYRAZOLE DERIVATIVE HCRTR1, HCRTR2, NPY4R CYP4F2 2278/4885CYP4A11 1266/4885ATR 4513/4885
US-20210147400-A1 METHOD FOR PRODUCING (2S)-2-[(1H-PYRAZOL-1-YL)METHYL]-1,3-OXAZINANE DERIVATIVE AGXT, GRHPR, HPD CYP4F2 317/4885CYP4A11 277/4885ATR 2179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.