SCHEMBL13734693

SCHEMBL13734693

CCO[CH]OC1CCCC1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6376511 0.98 EPHX1 (0.34) EPHX1
SCHEMBL3344028 0.93
SCHEMBL3349558 0.80 NAAA (0.33) EPHX1
SCHEMBL6178787 0.76
SCHEMBL6178352 0.76 CA1 (0.32)
SCHEMBL6181352 0.73 CA1 (0.36) EPHX1
SCHEMBL3349536 0.73 SMN1; SMN2 (0.36)
SCHEMBL2582250 0.72
SCHEMBL765983 0.70 EPHX1 (0.38) EPHX1
SCHEMBL6383370 0.70 EPHX1 (0.38) EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140024527-A1 HERBICIDAL PYRAZINONES E I DU DE NEMOURS AND COMPANY (US) 2014-01-23 US disclosed
WO-2012148622-A1 HERBICIDAL PYRAZINONES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-11-01 WO disclosed
CN-101466688-A Oxazole derivatives and their use in the treatment of diabetes and obesity ASTRAZENECA AB (SE) 2009-06-24 CN disclosed
CN-101115731-A Oxadiazole derivatives as DGAT inhibitors ASTRAZENECA AB (SE) 2008-01-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140024527-A1 HERBICIDAL PYRAZINONES CYP1B1, CBR3, CYP1A1 EPHX1 222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.