Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 5/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | RXRG | P48443 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13733290 | 0.87 | IKBKB (0.35) | IKBKBPPARDS1PR1PPARAPPARG | |
| SCHEMBL13732676 | 0.83 | IKBKB (0.35) | IKBKBPPARDPPARAPPARGPTPN1 | |
| SCHEMBL13732620 | 0.82 | IKBKB (0.34) | IKBKBPPARDPTPN1CHEK2SCN9A | |
| SCHEMBL13733889 | 0.81 | S1PR1 (0.40) | IKBKBS1PR1PPARAPPARGCHEK2 | |
| SCHEMBL13733126 | 0.79 | KMT2A (0.34) | IKBKBSCN9A | |
| SCHEMBL13732617 | 0.78 | IKBKB (0.34) | IKBKBPTPN1CHEK2SCN9A | |
| SCHEMBL13734891 | 0.78 | IKBKB (0.35) | IKBKBPTPN1CHEK2TRPV1SCN9A | |
| SCHEMBL15278210 | 0.77 | PPARD (0.41) | IKBKBPPARDPPARAPTPN1CHEK2 | |
| SCHEMBL13731883 | 0.76 | PPARD (0.37) | PPARDPPARAPPARGSCN9A | |
| SCHEMBL13734283 | 0.76 | IKBKB (0.34) | IKBKBPPARDS1PR1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699557-A1 | AROMATIC AMIDES AND USES THEREOF | Biota Scientific Management Pty Ltd (AU) | 2014-02-26 | — | — | EP | claimed |
| WO-2012142671-A1 | AROMATIC AMIDES AND USES THEREOF | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2012-10-26 | — | — | WO | claimed |