Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13732923 | 0.89 | S1PR1 (0.37) | S1PR1S1PR3PARP1SCN9A | |
| SCHEMBL13731435 | 0.86 | S1PR1 (0.39) | S1PR1S1PR3PARP1IKBKBCASP1 | |
| SCHEMBL13733290 | 0.81 | IKBKB (0.35) | S1PR1SCN9AIKBKBPPARGPPARA | |
| SCHEMBL13732543 | 0.81 | SCN9A (0.35) | S1PR1S1PR3PARP1SCN9AIKBKB | |
| SCHEMBL13734892 | 0.81 | IKBKB (0.35) | S1PR1SCN9AIKBKBPPARGPPARA | |
| SCHEMBL13732676 | 0.81 | IKBKB (0.35) | IKBKBCASP1PPARGPPARA | |
| SCHEMBL203408 | 0.80 | HSD17B1 (0.33) | S1PR1S1PR3SCN9A | |
| SCHEMBL2706695 | 0.79 | MAPT (0.37) | S1PR1S1PR3SCN9A | |
| SCHEMBL17275080 | 0.79 | HDAC3 (0.52) | — | |
| SCHEMBL13732485 | 0.78 | SCN9A (0.39) | S1PR1S1PR3SCN9ACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699557-A1 | AROMATIC AMIDES AND USES THEREOF | Biota Scientific Management Pty Ltd (AU) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012142671-A1 | AROMATIC AMIDES AND USES THEREOF | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2012-10-26 | — | — | WO | disclosed |