Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13518147 | 0.90 | GRM5 (0.64) | GRM5 | |
| SCHEMBL13518491 | 0.80 | GRM5 (0.68) | GRM5 | |
| SCHEMBL13518656 | 0.79 | GRM5 (0.64) | GRM5 | |
| SCHEMBL13518736 | 0.78 | GRM5 (0.61) | GRM5 | |
| SCHEMBL13519225 | 0.73 | GRM5 (0.55) | GRM5 | |
| SCHEMBL13559661 | 0.72 | PGR (0.41) | GRM5 | |
| SCHEMBL13518156 | 0.70 | GRM5 (0.59) | GRM5 | |
| SCHEMBL2518400 | 0.70 | GRM5 (1.00) | GRM5 | |
| SCHEMBL13518154 | 0.67 | GRM5 (0.67) | GRM5 | |
| SCHEMBL2516878 | 0.67 | GRM5 (1.00) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2702050-A1 | PYRAZOLIDIN-3-ONE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2014-03-05 | — | — | EP | disclosed |
| WO-2012146552-A1 | PYRAZOLIDIN-3-ONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-11-01 | — | — | WO | disclosed |