Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 16/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 12/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CASP1 | P29466 | 10/20 | 0.38 |
| ▸ | CASP7 | P55210 | 10/20 | 0.38 |
| ▸ | USP2 | O75604 | 6/20 | 0.38 |
| ▸ | GLA | P06280 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13736433 | 0.82 | CYP1A2 (0.38) | CYP1A2CYP3A4HSD17B10ALDH1A1CYP2C9 | |
| SCHEMBL13736743 | 0.80 | CYP1A2 (0.49) | CYP1A2CYP3A4HSD17B10ALDH1A1CYP2C9 | |
| SCHEMBL13733869 | 0.79 | CYP1A2 (0.48) | CYP1A2CYP3A4HSD17B10ALDH1A1CYP2C9 | |
| SCHEMBL13737520 | 0.76 | ALDH1A1 (0.42) | CYP1A2CYP3A4HSD17B10ALDH1A1CYP2C9 | |
| SCHEMBL457304 | 0.67 | TDP1 (0.39) | CYP1A2CYP3A4HSD17B10ALDH1A1CYP2C9 | |
| SCHEMBL15570252 | 0.66 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL9895127 | 0.65 | CYP1A2 (0.47) | CYP1A2CYP3A4HSD17B10ALDH1A1CYP2C9 | |
| SCHEMBL16435041 | 0.65 | KMT2A (0.36) | ALDH1A1MEN1KMT2AGRIN2BL3MBTL1 | |
| SCHEMBL454637 | 0.64 | CYP1A2 (0.40) | CYP1A2CYP3A4HSD17B10ALDH1A1CYP2C9 | |
| SCHEMBL14715247 | 0.64 | CYP1A2 (0.46) | CYP1A2CYP3A4HSD17B10ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140024527-A1 | HERBICIDAL PYRAZINONES | E I DU DE NEMOURS AND COMPANY (US) | 2014-01-23 | — | — | US | claimed |
| WO-2012148622-A1 | HERBICIDAL PYRAZINONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-01 | — | — | WO | claimed |
| US-20140024527-A1 | HERBICIDAL PYRAZINONES | E I DU DE NEMOURS AND COMPANY (US) | 2014-01-23 | — | — | US | disclosed |
| WO-2012148622-A1 | HERBICIDAL PYRAZINONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140024527-A1 | HERBICIDAL PYRAZINONES | CYP1B1, CBR3, CYP1A1 | CYP1A2 7/4885CYP3A4 15/4885HSD17B10 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.