SCHEMBL13740263

SCHEMBL13740263

NC1CCN(C(F)C(F)F)C1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4D Q6B0I6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29243574 1.00 KDM4D (0.32) KDM4D
SCHEMBL28999393 0.86
Hydrochloric Acid SCHEMBL29270802 0.85
Hydrochloric Acid SCHEMBL29143934 0.84 GNAI3 (0.31)
SCHEMBL680926 0.71
SCHEMBL2428595 0.71
SCHEMBL1306188 0.71
SCHEMBL1700039 0.71
SCHEMBL1700037 0.71
SCHEMBL29044516 0.70 GNAI3 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2678329-A1 TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS Array Biopharma, Inc. (US) 2014-01-01 EP disclosed
WO-2012154274-A1 TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS ARRAY BIOPHARMA INC. (US) 2012-11-15 WO disclosed