Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK11 | Q15759 | 17/20 | 0.80 |
| ▸ | MAPK14 | Q16539 | 17/20 | 0.80 |
| ▸ | MAPK13 | O15264 | 16/20 | 0.80 |
| ▸ | MAPK12 | P53778 | 16/20 | 0.80 |
| ▸ | ALOX5 | P09917 | 13/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.80 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.80 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.80 |
| ▸ | GMNN | O75496 | 2/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.80 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.80 |
| ▸ | THPO | P40225 | 2/20 | 0.80 |
| ▸ | BLM | P54132 | 2/20 | 0.80 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pd-169316 SCHEMBL154958 | 0.89 | MAPK14 (1.00) | MAPK11MAPK14MAPK13MAPK12ALOX5 | |
| Pd-169316 SCHEMBL9899161 | 0.89 | MAPK14 (1.00) | MAPK11MAPK14MAPK13MAPK12ALOX5 | |
| SCHEMBL19868925 | 0.88 | MAPK11 (1.00) | MAPK11MAPK14MAPK13MAPK12ALOX5 | |
| SCHEMBL15075603 | 0.88 | MAPK11 (1.00) | MAPK11MAPK14MAPK13MAPK12ALOX5 | |
| SCHEMBL2650684 | 0.84 | MAPK11 (1.00) | MAPK11MAPK14MAPK13MAPK12ALOX5 | |
| SCHEMBL4552316 | 0.82 | MAPK14 (1.00) | MAPK11MAPK14MAPK13MAPK12ALOX5 | |
| SCHEMBL9195042 | 0.82 | MAPK14 (1.00) | MAPK11MAPK14MAPK13MAPK12ALOX5 | |
| SCHEMBL2650702 | 0.82 | MAPK11 (1.00) | MAPK11MAPK14MAPK13MAPK12ALOX5 | |
| SCHEMBL20335253 | 0.82 | MAPK11 (0.81) | MAPK11MAPK14MAPK13MAPK12ALOX5 | |
| SCHEMBL6469126 | 0.81 | MAPK13 (1.00) | MAPK11MAPK14MAPK13MAPK12ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102498-A1 | NOVEL IMAGING AGENTS FOR DETECTING NEUROLOGICAL DYSFUNCTION | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2009-08-20 | — | — | WO | disclosed |