Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK11 | Q15759 | 17/20 | 0.81 |
| ▸ | MAPK14 | Q16539 | 17/20 | 0.81 |
| ▸ | MAPK13 | O15264 | 16/20 | 0.81 |
| ▸ | MAPK12 | P53778 | 16/20 | 0.81 |
| ▸ | GCGR | P47871 | 14/20 | 0.81 |
| ▸ | CSNK1A1 | P48729 | 5/20 | 0.81 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.81 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.81 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.81 |
| ▸ | FRK | P42685 | 4/20 | 0.81 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.81 |
| ▸ | GSK3B | P49841 | 4/20 | 0.81 |
| ▸ | PTK6 | Q13882 | 3/20 | 0.81 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.81 |
| ▸ | PRKD2 | Q9BZL6 | 3/20 | 0.81 |
| ▸ | ALOX5 | P09917 | 13/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15075603 | 0.90 | MAPK11 (1.00) | MAPK11MAPK14MAPK13MAPK12GCGR | |
| SCHEMBL19868925 | 0.90 | MAPK11 (1.00) | MAPK11MAPK14MAPK13MAPK12GCGR | |
| SCHEMBL21519839 | 0.85 | MAPK11 (0.73) | MAPK11MAPK14MAPK13MAPK12GCGR | |
| SCHEMBL2650702 | 0.85 | MAPK11 (1.00) | MAPK11MAPK14MAPK13MAPK12GCGR | |
| SCHEMBL4552316 | 0.85 | MAPK14 (1.00) | MAPK11MAPK14MAPK13MAPK12GCGR | |
| SCHEMBL9195042 | 0.85 | MAPK14 (1.00) | MAPK11MAPK14MAPK13MAPK12GCGR | |
| SCHEMBL2649616 | 0.83 | MAPK13 (1.00) | MAPK11MAPK14MAPK13MAPK12GCGR | |
| SCHEMBL2648930 | 0.83 | MAPK13 (1.00) | MAPK11MAPK14MAPK13MAPK12GCGR | |
| Sb-202190 SCHEMBL3386753 | 0.83 | MAPK13 (1.00) | MAPK11MAPK14MAPK13MAPK12GCGR | |
| SCHEMBL2648969 | 0.83 | MAPK13 (1.00) | MAPK11MAPK14MAPK13MAPK12GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342858-B1 | ROR1-POSITIVE MESENCHYMAL STEM CELLS AND METHOD FOR PREPARING SAME, PHARMACEUTICAL COMPOSITION CONTAINING ROR1-POSITIVE MESENCHYMAL STEM CELLS AND METHOD FOR PREPARING SAME, AND METHOD FOR PREVENTING OR TREATING DISEASES BY USING ROR1-POSITIVE MESENCHYMAL STEM CELLS | ROHTO PHARMA (JP) | 2023-10-04 | — | — | EP | disclosed |
| US-11707488-B2 | ROR1-positive mesenchymal stem cells and method for preparing same, pharmaceutical composition containing ROR1-positive mesenchymal stem cells and method for preparing same, and method for preventing or treating disease using ROR1-positive mesenchymal stem cells | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2023-07-25 | — | — | US | disclosed |
| CN-108350427-B | ROR1 positive mesenchymal stem cells and pharmaceutical composition comprising same | 日本乐敦制药株式会社 | 2022-03-11 | — | — | CN | disclosed |
| US-20200069740-A1 | ROR1-POSITIVE MESENCHYMAL STEM CELL-CONTAINING PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DISEASE ASSOCIATED WITH FIBROSIS, METHOD FOR PREPARING SAME, AND METHOD FOR PREVENTING OR TREATING DISEASE ASSOCIATED WITH FIBROSIS USING ROR1-POSITIVE MESENCHYMAL STEM CELLS | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2020-03-05 | — | — | US | disclosed |
| US-20180333436-A1 | ROR1-POSITIVE MESENCHYMAL STEM CELLS AND METHOD FOR PREPARING SAME, PHARMACEUTICAL COMPOSITION CONTAINING ROR1-POSITIVE MESENCHYMAL STEM CELLS AND METHOD FOR PREPARING SAME, AND METHOD FOR PREVENTING OR TREATING DISEASE USING ROR1-POSITIVE MESENCHYMAL STEM CELLS | ROHTO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-22 | — | — | US | disclosed |
| EP-3342858-A1 | ROR1-POSITIVE MESENCHYMAL STEM CELLS AND METHOD FOR PREPARING SAME, PHARMACEUTICAL COMPOSITION CONTAINING ROR1-POSITIVE MESENCHYMAL STEM CELLS AND METHOD FOR PREPARING SAME, AND METHOD FOR PREVENTING OR TREATING DISEASES BY USING ROR1-POSITIVE MESENCHYMAL STEM CELLS | Rohto Pharmaceutical Co., Ltd. (JP) | 2018-07-04 | — | — | EP | disclosed |