Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.46 |
| ▸ | PNLIP | P16233 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13742651 | 0.90 | KDM4E (0.72) | KDM4EPTGDR2NR1H4MEN1NPC1 | |
| SCHEMBL13742260 | 0.88 | KDM4E (0.58) | KDM4EKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL13742068 | 0.88 | KDM4E (0.58) | KDM4EKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL13742003 | 0.88 | KDM4E (0.64) | KDM4EKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL13742693 | 0.88 | KDM4E (0.67) | KDM4EPTGDR2NR1H4MEN1NPC1 | |
| SCHEMBL2981115 | 0.87 | KDM4E (0.66) | KDM4EPTGDR2NR1H4MEN1MAPT | |
| SCHEMBL13742527 | 0.85 | KDM4E (0.55) | KDM4EKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL8915769 | 0.85 | KDM4E (0.53) | KDM4EKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL3137838 | 0.85 | KDM4E (0.53) | KDM4EKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL12761132 | 0.85 | KDM4E (0.64) | KDM4EPTGDR2NR1H4MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009096526-A1 | CARBOXYLIC ACID COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-08-06 | — | — | WO | disclosed |