Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.45 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13742001 | 0.88 | KDM4E (0.67) | KDM4EMEN1NPC1RAB9AKMT2A | |
| SCHEMBL13742686 | 0.88 | KDM4E (0.64) | KDM4EMEN1NPC1RAB9AKMT2A | |
| SCHEMBL13742071 | 0.87 | MAPT (0.48) | KDM4EMEN1NPC1RAB9AKMT2A | |
| SCHEMBL13742651 | 0.86 | KDM4E (0.72) | KDM4EMEN1NPC1RAB9AKMT2A | |
| SCHEMBL13742068 | 0.83 | KDM4E (0.58) | KDM4ENPC1RAB9APTGDR2KCNQ3 | |
| SCHEMBL13742260 | 0.83 | KDM4E (0.58) | KDM4EPTGDR2KCNQ3KCNQ2KCNE1 | |
| SCHEMBL13742510 | 0.82 | KDM4E (0.62) | KDM4EMEN1NPC1RAB9AKMT2A | |
| SCHEMBL13742500 | 0.82 | KDM4E (0.61) | KDM4EMEN1NPC1RAB9AKMT2A | |
| SCHEMBL13742527 | 0.81 | KDM4E (0.55) | KDM4EPTGDR2PTGDRKCNQ3KCNQ2 | |
| SCHEMBL8915769 | 0.81 | KDM4E (0.53) | KDM4EMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009096526-A1 | CARBOXYLIC ACID COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-08-06 | — | — | WO | disclosed |