⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1373488 | 0.97 | MEN1 (0.50) | — | |
| SCHEMBL7244900 | 0.77 | ALDH1A1 (0.57) | — | |
| SCHEMBL1372330 | 0.77 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL4924066 | 0.77 | — | — | |
| SCHEMBL101925 | 0.77 | — | — | |
| SCHEMBL426509 | 0.74 | MEN1 (0.55) | — | |
| SCHEMBL425336 | 0.74 | MEN1 (0.55) | — | |
| SCHEMBL9407486 | 0.74 | KMT2A (0.55) | — | |
| SCHEMBL13635633 | 0.74 | MEN1 (0.55) | — | |
| SCHEMBL16687885 | 0.74 | MEN1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2592083-A1 | FUSED QUINAZOLINE DERIVATIVES AND USES THEREOF | Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) | 2013-05-15 | — | — | EP | claimed |
| US-20110288086-A1 | POLYCYCLIC QUINAZOLINES, PREPARATION THEREOF, AND USE THEREOF | SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD. (CN) | 2011-11-24 | — | — | US | claimed |
| EP-0764150-B1 | PRODUCTION OF HYDROXYTHIOACETAMIDES AND USE THEREOF IN THE SYNTHESIS OF BENZOTHIOPHENES | LILLY CO ELI (US) | 1999-10-27 | — | — | EP | claimed |
| EP-2592083-A1 | FUSED QUINAZOLINE DERIVATIVES AND USES THEREOF | Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) | 2013-05-15 | — | — | EP | disclosed |
| US-20110288086-A1 | POLYCYCLIC QUINAZOLINES, PREPARATION THEREOF, AND USE THEREOF | SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD. (CN) | 2011-11-24 | — | — | US | disclosed |
| US-5928981-A | MIXTURE OF ZEOLITES AND METAL OXIDE OF ALUMINUM SILICATE, ALUMINA AND/OR TITANIA HAVING PLATINUM GROUP METAL DEPOSITED ONLY ON METAL OXIDE | DEGUSSA-HULS AKTIENGESELLSCHAFT (DE) | 1999-07-27 | — | — | US | disclosed |