Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.84 |
| ▸ | MAPT | P10636 | 12/20 | 0.78 |
| ▸ | MEN1 | O00255 | 5/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.78 |
| ▸ | TSHR | P16473 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 6/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | DHODH | Q02127 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13744563 | 0.91 | MAPT (0.78) | POLBMAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL13744821 | 0.90 | MEN1 (0.70) | POLBMAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL13744022 | 0.90 | KMT2A (0.70) | POLBMAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL13744482 | 0.89 | MAPT (0.87) | POLBMAPTMEN1KMT2AHSD17B10 | |
| Iodide SCHEMBL2950070 | 0.84 | MEN1 (0.61) | POLBMAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL20473331 | 0.81 | MAPT (1.00) | POLBMAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL13744643 | 0.80 | HSD17B10 (0.66) | POLBMAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL13744565 | 0.79 | KMT2A (0.57) | POLBMAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL13744689 | 0.79 | KMT2A (0.59) | POLBMAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL2940128 | 0.79 | SMN1; SMN2 (0.59) | POLBMAPTMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209511-A1 | Benzofuran Derivatives | KAWAGUCHI TAKAYUKI | 2009-08-20 | — | — | US | disclosed |
| US-20090209511-A1 | Benzofuran Derivatives | KAWAGUCHI TAKAYUKI | 2009-08-20 | — | — | US | disclosed |
| US-7531537-B2 | Benzofuran derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209511-A1 | Benzofuran Derivatives | F12, F2, F3 | POLB 1805/4885MAPT 4681/4885MEN1 2864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.