SCHEMBL20473331

SCHEMBL20473331

COc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)C2CC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 12/20 1.00
▸ MEN1 O00255 7/20 1.00
▸ KMT2A Q03164 7/20 1.00
▸ HSD17B10 Q99714 5/20 1.00
▸ TSHR P16473 5/20 1.00
▸ KDM4E B2RXH2 5/20 1.00
▸ ALDH1A1 P00352 4/20 1.00
▸ HPGD P15428 2/20 1.00
▸ ALOX15 P16050 1/20 1.00
▸ HTT P42858 1/20 1.00
▸ NPSR1 Q6W5P4 3/20 0.79
▸ SMN1; SMN2 Q16637 2/20 0.79
▸ LMNA P02545 1/20 0.79
▸ DHODH Q02127 1/20 0.79
▸ POLB P06746 2/20 0.74
▸ TP53 P04637 5/20 0.72
▸ MAPK1 P28482 1/20 0.70
▸ GAA P10253 1/20 0.66
▸ RXFP1 Q9HBX9 1/20 0.64
▸ USP2 O75604 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13744482 0.93 MAPT (0.87) MAPTMEN1KMT2AHSD17B10TSHR
SCHEMBL13744563 0.81 MAPT (0.78) MAPTMEN1KMT2AHSD17B10TSHR
SCHEMBL13744413 0.81 MEN1 (0.74) MAPTMEN1KMT2AHSD17B10TSHR
SCHEMBL13744566 0.81 POLB (0.84) MAPTMEN1KMT2AHSD17B10TSHR
SCHEMBL13744691 0.81 MEN1 (0.70) MAPTMEN1KMT2AHSD17B10TSHR
SCHEMBL13744022 0.81 KMT2A (0.70) MAPTMEN1KMT2AHSD17B10TSHR
SCHEMBL13744821 0.81 MEN1 (0.70) MAPTMEN1KMT2AHSD17B10TSHR
Hydrochloric Acid SCHEMBL2950217 0.80 MEN1 (0.72) MAPTMEN1KMT2AHSD17B10TSHR
Hydrochloric Acid SCHEMBL2950215 0.80 MEN1 (0.72) MAPTMEN1KMT2AHSD17B10TSHR
SCHEMBL13744976 0.79 MEN1 (0.67) MAPTMEN1KMT2AHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108351537-A Function glasses eyeglass for block ultraviolet and blue light 凯米格拉斯公司 2018-07-31 — — CN claimed
US-20190025465-A1 FUNCTIONAL EYEGLASS LENS FOR BLOCKING ULTRAVIOLET AND BLUE LIGHT Chemiglass Corporation (KR) 2019-01-24 — — US disclosed
EP-3364236-A1 FUNCTIONAL EYEGLASS LENS FOR BLOCKING ULTRAVIOLET AND BLUE LIGHT Chemiglas Corporation (KR) 2018-08-22 — — EP disclosed
CN-108351537-A Function glasses eyeglass for block ultraviolet and blue light 凯米格拉斯公司 2018-07-31 — — CN disclosed
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