Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | VNN1 | O95497 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26691463 | 0.94 | CCR5 (0.40) | DPP4KCNH2DPP8DPP9CCR5 | |
| SCHEMBL26691466 | 0.92 | CCR5 (0.43) | DPP4KCNH2DPP8DPP9CCR5 | |
| SCHEMBL8259194 | 0.92 | CCR5 (0.43) | DPP4KCNH2DPP8DPP9CCR5 | |
| SCHEMBL17192615 | 0.91 | DPP4 (0.43) | DPP4KCNH2DPP8DPP9CCR5 | |
| SCHEMBL14168117 | 0.91 | DPP4 (0.36) | DPP4KCNH2DPP8DPP9CCR5 | |
| SCHEMBL13176020 | 0.90 | CCR5 (0.42) | DPP4KCNH2DPP8DPP9CCR5 | |
| SCHEMBL24511498 | 0.85 | DPP4 (0.33) | DPP4KCNH2DPP8DPP9 | |
| SCHEMBL9001736 | 0.84 | DPP4 (0.40) | DPP4KCNH2DPP8DPP9CCR5 | |
| SCHEMBL24342363 | 0.84 | SOS1 (0.32) | DPP4KCNH2DPP8DPP9CCR5 | |
| SCHEMBL9001740 | 0.81 | CCR5 (0.47) | DPP4KCNH2DPP8DPP9CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209511-A1 | Benzofuran Derivatives | KAWAGUCHI TAKAYUKI | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209511-A1 | Benzofuran Derivatives | F12, F2, F3 | DPP4 2709/4885KCNH2 1056/4885DPP8 3132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.