SCHEMBL1374510

SCHEMBL1374510

O=S(=O)(O)C(O)c1ccccn1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
NPSR1 Q6W5P4 1/20 0.47
SLC6A3 Q01959 2/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A4 P31645 1/20 0.45
TP53 P04637 1/20 0.42
RECQL P46063 1/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ALDH1A1 P00352 1/20 0.41
KCNA5 P22460 3/20 0.40
TSHR P16473 2/20 0.40
MAPT P10636 1/20 0.40
KCNE1 P15382 1/20 0.40
SLC10A1 Q14973 1/20 0.40
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29486367 1.00 KDM4E (0.49) KDM4ENPSR1SLC6A3SLC6A2SLC6A4
SCHEMBL2375133 0.84 KDM4E (0.50) KDM4ENPSR1SLC6A3SLC6A2SLC6A4
SCHEMBL4807002 0.80 CYP1A2 (0.47) KDM4ENPSR1SLC6A3SLC6A2SLC6A4
SCHEMBL28001481 0.80 SLC6A3 (0.42) KDM4ENPSR1SLC6A3SLC6A2SLC6A4
SCHEMBL14571412 0.80 KDM4E (0.42) KDM4ENPSR1SLC6A3SLC6A2SLC6A4
SCHEMBL27652094 0.79 CYP1A2 (0.46) KDM4ENPSR1SLC6A3SLC6A2SLC6A4
SCHEMBL11551880 0.79 CYP1A2 (0.46) KDM4ENPSR1SLC6A3SLC6A2SLC6A4
SCHEMBL27652093 0.79 CYP1A2 (0.46) KDM4ENPSR1SLC6A3SLC6A2SLC6A4
SCHEMBL27996727 0.77 SLC6A2 (0.53) KDM4ENPSR1SLC6A3SLC6A2SLC6A4
SCHEMBL28225638 0.77 KDM4E (0.44) KDM4ENPSR1SLC6A3SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110163411-B Operation optimization method for regional comprehensive energy system 华北电力大学 2022-02-18 CN claimed
CN-113557239-A Oligosaccharide formulations and compositions 米德瑞美国有限公司 2021-10-26 CN claimed
EP-3880688-A1 OLIGOSACCHARIDE PREPARATIONS AND COMPOSITIONS Midori USA, Inc. (US) 2021-09-22 EP claimed
EP-1947159-B1 Adsorption of vanadium compounds from fuel oil GEN ELECTRIC (US) 2016-12-07 EP claimed
US-20130052315-A1 Methods and Compositions for Protecting Beverages From Heat and Light Stress PEPSICO, INC. (US) 2013-02-28 US claimed
WO-2013028314-A1 METHODS AND COMPOSITIONS FOR PROTECTING BEVERAGES FROM HEAT AND LIGHT STRESS PEPSICO, INC. (US) 2013-02-28 WO claimed
US-20080169221-A1 ADSORPTION OF VANADIUM COMPOUNDS FROM FUEL OIL AND ADSORBENTS THEREOF GE INFRASTRUCTURE TECHNOLOGY LLC 2008-07-17 US claimed
US-7105214-B2 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION (US) 2006-09-12 US claimed
US-20030124320-A1 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION 2003-07-03 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0673782-B1 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORP (US) 2000-06-14 EP claimed
US-5657064-A Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION (US) 1997-08-12 US claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673782-A2 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
US-4793987-A Stabilized radiolabelled compounds AMERSHAM INTERNATIONAL PLC (GB) 1988-12-27 US claimed
EP-0203696-A2 Stabilized radiolabelled compounds AMERSHAM INTERNATIONAL plc (GB) 1986-12-03 EP claimed