Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13744725 | 0.90 | KDM4E (0.44) | KDM4EMAPTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL13744715 | 0.88 | KDM4E (0.45) | KDM4EMAPTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL13744750 | 0.86 | KDM4E (0.44) | KDM4EMAPTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL13745242 | 0.85 | ALDH1A1 (0.44) | KDM4EMAPTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL13744755 | 0.82 | KDM4E (0.44) | KDM4EMAPTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL13744729 | 0.81 | KDM4E (0.47) | KDM4EMAPTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL13745134 | 0.79 | KDM4E (0.44) | KDM4EMAPTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL13744803 | 0.77 | KDM4E (0.44) | KDM4EMAPTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL13744868 | 0.72 | KDM4E (0.44) | KDM4EMAPTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL13745008 | 0.72 | ALDH1A1 (0.45) | KDM4EMAPTTSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097144-A1 | MOLECULAR PROBES FOR PET-IMAGING OF DOPAMINE NEUROTRANSMISSION AND NEUROENDOCRINE PROCESSES IN VIVO | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-08-06 | — | — | WO | disclosed |