Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6367851 | 0.88 | MAPT (0.51) | MAPTCYP4Z1MAOBGAAABCB1 | |
| SCHEMBL6372557 | 0.83 | MAPT (0.48) | MAPTCYP4Z1MAOBGAAALDH1A1 | |
| SCHEMBL13745785 | 0.83 | HSP90AB1 (0.53) | MAPTGAAALDH1A1MEN1HPGD | |
| SCHEMBL137425 | 0.82 | HSP90AB1 (0.51) | MAPTCYP4Z1MAOBGAAALDH1A1 | |
| SCHEMBL134983 | 0.81 | MAPT (0.46) | MAPTCYP4Z1MAOBGAAABCB1 | |
| SCHEMBL10218934 | 0.81 | CYP4F2 (0.47) | MAPTCYP4Z1MAOBGAAALDH1A1 | |
| SCHEMBL27748102 | 0.78 | MAPT (0.44) | MAPTCYP4Z1MAOBGAAALDH1A1 | |
| SCHEMBL12135664 | 0.77 | GPR35 (0.47) | MAPTCYP4Z1MAOBGAAALDH1A1 | |
| SCHEMBL24690441 | 0.76 | MAPT (0.47) | MAPTCYP4Z1GAAALDH1A1KDM4E | |
| SCHEMBL12020856 | 0.75 | SMN1; SMN2 (0.45) | MAPTCYP4Z1MAOBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099902-A1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |