Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | PTPRF | P10586 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21969580 | 0.80 | ALDH1A1 (0.47) | TDP1ALDH1A1ALOX15SRCKDM4E | |
| SCHEMBL22624389 | 0.79 | MEN1 (0.42) | MEN1KMT2ATDP1ALDH1A1ALOX15 | |
| SCHEMBL16994141 | 0.78 | MEN1 (0.42) | MEN1KMT2ATDP1ALDH1A1ALOX15 | |
| SCHEMBL7765253 | 0.77 | MEN1 (0.41) | MEN1KMT2ATDP1ALDH1A1ALOX15 | |
| SCHEMBL22991616 | 0.77 | MEN1 (0.41) | MEN1KMT2ATDP1ALDH1A1ALOX15 | |
| SCHEMBL29712372 | 0.77 | MEN1 (0.41) | MEN1KMT2ATDP1ALDH1A1ALOX15 | |
| SCHEMBL6472175 | 0.77 | MEN1 (0.50) | MEN1KMT2ATDP1ALDH1A1ALOX15 | |
| SCHEMBL4088432 | 0.75 | MEN1 (0.46) | MEN1KMT2ATDP1ALDH1A1ALOX15 | |
| SCHEMBL30516691 | 0.74 | ALDH1A1 (0.65) | MEN1KMT2ATDP1ALDH1A1ALOX15 | |
| SCHEMBL40612 | 0.74 | ALDH1A1 (0.65) | MEN1KMT2ATDP1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572829-B2 | Pharmaceutical compositions useful in prevention and treatment of Beta-amyloid protein-induced disease | KIM DARRICK S H L | 2009-08-11 | — | — | US | disclosed |
| US-20080085932-A1 | Pharmaceutical Compositions Useful In Prevention and Treatment of Beta-Amyloid Protein-Induced Disease | KIM DARRICK S | 2008-04-10 | — | — | US | disclosed |
| US-7282523-B2 | Pharmaceutical compositions useful in prevention and treatment of beta-amyloid protein-induced disease | KIM DARRICK S H L | 2007-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085932-A1 | Pharmaceutical Compositions Useful In Prevention and Treatment of Beta-Amyloid Protein-Induced Disease | APP, BACE1, PSEN1 | MEN1 882/4885KMT2A 4502/4885TDP1 3704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.