Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ACACB | O00763 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19884283 | 0.88 | RECQL (0.87) | RECQLTP53SMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL15038846 | 0.88 | RECQL (0.87) | RECQLTP53SMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL14314483 | 0.88 | RECQL (0.87) | RECQLTP53SMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL23996271 | 0.86 | ACACB (0.57) | RECQLTP53SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9057935 | 0.84 | RECQL (0.94) | RECQLTP53SMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL20663584 | 0.84 | RECQL (1.00) | RECQLTP53SMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL15038847 | 0.84 | RECQL (1.00) | RECQLTP53SMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL24423986 | 0.84 | SMN1; SMN2 (0.53) | RECQLTP53SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL21444578 | 0.83 | RECQL (0.91) | RECQLTP53SMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL517633 | 0.83 | RECQL (0.91) | RECQLTP53SMN1; SMN2ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098282-A1 | LOW MOLECULAR WEIGHT 2,5-DISUBSTITUTED THIOPHENE DERIVATIVES AND USE THEREOF IN THERAPY | NOVASAID AB (SE) | 2009-08-13 | — | — | WO | disclosed |