SCHEMBL13745559

SCHEMBL13745559

CCC(C)N1C(=O)NC(C)(C)C1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.45
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.37
TSHR P16473 2/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 2/20 0.36
ALDH1A1 P00352 2/20 0.36
PDE4A P27815 1/20 0.35
PDE4B Q07343 1/20 0.35
PDE4C Q08493 1/20 0.35
PDE4D Q08499 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GAA P10253 2/20 0.34
GLA P06280 1/20 0.34
HSD17B10 Q99714 2/20 0.34
AR P10275 1/20 0.33
KDM4E B2RXH2 1/20 0.33
PADI4 Q9UM07 1/20 0.32
PKM P14618 1/20 0.32
SIRT5 Q9NXA8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12042277 0.79 POLB (0.46) POLBKMT2AMEN1TSHRLMNA
SCHEMBL10422398 0.78 POLB (0.44) POLBKMT2AMEN1TSHRLMNA
SCHEMBL23417579 0.78 ALDH1A1 (0.41) POLBKMT2ALMNAMAPTALDH1A1
SCHEMBL21169208 0.75 POLB (0.43) POLBKMT2AMEN1TSHRLMNA
SCHEMBL11384762 0.75 POLB (0.43) POLBKMT2AMEN1TSHRLMNA
SCHEMBL4945315 0.74 POLB (0.40) POLBKMT2AMEN1TSHRLMNA
SCHEMBL11165303 0.73 POLB (0.36) POLBKMT2AMEN1TSHRLMNA
SCHEMBL1159787 0.72 POLB (0.45) POLBKMT2AMEN1TSHRLMNA
SCHEMBL4943217 0.72 POLB (0.38) POLBKMT2AMEN1TSHRLMNA
SCHEMBL10246364 0.71 ALDH1A1 (0.37) KMT2AMEN1MAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090197084-A1 BIOCIDAL FIBERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-08-06 US disclosed