Toluene

Toluene

SCHEMBL1374569

Cc1ccc(S(=O)(=O)NN)cc1.Cc1ccccc1

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 4/20 0.61
CA2 P00918 4/20 0.61
CA12 O43570 3/20 0.61
CA1 P00915 3/20 0.61
ALDH1A1 P00352 5/20 0.58
GAA P10253 3/20 0.58
CYP1A2 P05177 2/20 0.58
CYP3A4 P08684 2/20 0.58
CYP2C9 P11712 2/20 0.58
CYP2C19 P33261 2/20 0.58
KDM4E B2RXH2 1/20 0.58
CYP2D6 P10635 1/20 0.58
HPGD P15428 1/20 0.58
ALOX12 P18054 1/20 0.58
GFER P55789 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
L3MBTL1 Q9Y468 2/20 0.56
ATM Q13315 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.55
MEN1 O00255 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10778613 0.96 CA12 (0.61) CA9CA2CA12CA1ALDH1A1
SCHEMBL250755 0.92 GAA (0.64) CA9CA2CA12CA1ALDH1A1
SCHEMBL9091 0.92 GAA (0.64) CA9CA2CA12CA1ALDH1A1
Hydrochloric Acid SCHEMBL4639536 0.90 SMN1; SMN2 (0.61) CA9CA2CA12CA1ALDH1A1
SCHEMBL28554322 0.90 SMN1; SMN2 (0.61) CA9CA2CA12CA1ALDH1A1
Water SCHEMBL27947230 0.90 SMN1; SMN2 (0.61) CA9CA2CA12CA1ALDH1A1
Acetic Acid SCHEMBL27544357 0.86 CA1 (0.57) CA9CA2CA12CA1ALDH1A1
Benzaldehyde SCHEMBL28000926 0.86 CA12 (0.51) CA9CA2CA12CA1ALDH1A1
SCHEMBL8434833 0.85 PTPRC (0.57) CA9CA2CA12CA1ALDH1A1
Acetone SCHEMBL5923757 0.84 CA1 (0.59) CA9CA2CA12CA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150011440-A1 FOAM RESIN SEALANT FOR ZONAL ISOLATION AND METHODS FOR MAKING AND USING SAME CLEARWATER INTERNATIONAL, LLC (US) 2015-01-08 US claimed
US-8851174-B2 Foam resin sealant for zonal isolation and methods for making and using same CLEARWATER INTERNATIONAL LLC (US) 2014-10-07 US claimed
US-20150011440-A1 FOAM RESIN SEALANT FOR ZONAL ISOLATION AND METHODS FOR MAKING AND USING SAME CLEARWATER INTERNATIONAL, LLC (US) 2015-01-08 US disclosed
US-8851174-B2 Foam resin sealant for zonal isolation and methods for making and using same CLEARWATER INTERNATIONAL LLC (US) 2014-10-07 US disclosed
US-20110284248-A1 FOAM RESIN SEALANT FOR ZONAL ISOLATION AND METHODS FOR MAKING AND USING SAME CLEARWATER INTERNATIONAL, LLC (US) 2011-11-24 US disclosed