Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422893 | 0.97 | EPHX1 (0.42) | EPHX1LMNAALDH1A1TP53GRIA1 | |
| SCHEMBL3422719 | 0.90 | — | — | |
| SCHEMBL9185106 | 0.81 | ALDH1A1 (0.50) | LMNAALDH1A1TP53CA2NLRP3 | |
| SCHEMBL5461072 | 0.81 | ALDH1A1 (0.50) | LMNAALDH1A1TP53CA2NLRP3 | |
| SCHEMBL553402 | 0.78 | — | — | |
| SCHEMBL17333726 | 0.78 | ALDH1A1 (0.38) | LMNAALDH1A1TP53GRIA1PPARA | |
| SCHEMBL777321 | 0.78 | ALDH1A1 (0.52) | LMNAALDH1A1TP53CA2NLRP3 | |
| SCHEMBL6115755 | 0.77 | APP (0.46) | EPHX1LMNASIGMAR1KDM4AKDM4C | |
| SCHEMBL8350827 | 0.76 | EPHX1 (0.42) | EPHX1GRIA1SIGMAR1KDM4AKDM4C | |
| Hydrochloric Acid SCHEMBL1902590 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099736-A2 | BENZOXAZOLE CARBOXAMIDE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | LEAD THERAPEUTICS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |