Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | GJB2 | P29033 | 4/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | CD209 | Q9NNX6 | 1/20 | 0.32 |
| ▸ | IGF2R | P11717 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13806499 | 0.88 | TNF (0.40) | TNFGJB2CD209 | |
| SCHEMBL14900306 | 0.88 | TNF (0.40) | TNFGJB2CD209 | |
| SCHEMBL15296514 | 0.88 | TNF (0.40) | TNFGJB2CD209 | |
| SCHEMBL14817730 | 0.88 | TNF (0.40) | TNFGJB2CD209 | |
| SCHEMBL15482156 | 0.87 | GJB2 (0.37) | TNFGJB2GBA1 | |
| SCHEMBL16351048 | 0.87 | GJB2 (0.37) | TNFGJB2GBA1 | |
| SCHEMBL14864775 | 0.87 | TNF (0.37) | TNFGJB2IGF2R | |
| SCHEMBL13806497 | 0.86 | GJB2 (0.40) | TNFGJB2SSTR1SSTR2SSTR4 | |
| SCHEMBL18948258 | 0.86 | GJB2 (0.37) | TNFGJB2 | |
| SCHEMBL14554179 | 0.82 | GJB2 (0.37) | TNFGJB2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317846-A1 | Production Of L-Iduronate Containing Polysaccharides | THE UNIVERSITY OF MANCHESTER (GB) | 2010-12-16 | — | — | US | disclosed |
| WO-2009098449-A1 | PRODUCTION OF L-IDURONATE CONTAINING POLYSACCHARIDES | THE UNIVERSITY OF MANCHESTER (GB) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317846-A1 | Production Of L-Iduronate Containing Polysaccharides | IDUA, IDO1, IDO2 | TNF 2484/4885GJB2 4854/4885SSTR1 1355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.