Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | ESRRB | O95718 | 1/20 | 0.31 |
| ▸ | ESRRA | P11474 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13746942 | 0.77 | NPY5R (0.39) | NPY5RMAPTTYMS | |
| SCHEMBL1484851 | 0.70 | PIK3CA (0.46) | LMNAMAPTHTTBLMPIK3CA | |
| SCHEMBL16438129 | 0.69 | NPY5R (0.46) | NPY5RMAPTMAOBPIK3CAPIK3CB | |
| SCHEMBL14743532 | 0.69 | NPY5R (0.36) | NPY5RPPARAMAOBPIK3CAPIK3CB | |
| SCHEMBL14743237 | 0.68 | NPY5R (0.36) | NPY5RPPARAMAOBPIK3CAMAP3K5 | |
| SCHEMBL10182520 | 0.68 | PPARA (0.37) | NPY5RPPARAPIK3CAPIK3CBPIK3CG | |
| SCHEMBL1484798 | 0.68 | KDM4E (0.48) | LMNAMAPTPIK3CAPIK3CBPIK3CG | |
| SCHEMBL1484697 | 0.68 | PIK3CA (0.47) | PIK3CAPIK3CBPIK3CGPIK3CD | |
| SCHEMBL10182368 | 0.67 | KMT2A (0.40) | PPARAPTGESLMNAMAPTHTT | |
| SCHEMBL1484989 | 0.67 | LMNA (0.38) | PPARAPTGESLMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102633-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-20 | — | — | WO | disclosed |