Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 7/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13746410 | 0.89 | TYMS (0.39) | TYMSACACBACACATRPV1PSD | |
| SCHEMBL13746960 | 0.87 | TYMS (0.39) | TYMSACACBACACATRPV1PSD | |
| SCHEMBL13746667 | 0.87 | PDE2A (0.37) | TYMSPDE2A | |
| SCHEMBL4192359 | 0.87 | PSD (0.38) | TYMSACACBACACATRPV1PSD | |
| SCHEMBL13746092 | 0.87 | PSD (0.38) | TYMSACACBACACATRPV1PSD | |
| SCHEMBL13746941 | 0.85 | EIF4E (0.36) | TYMSACACBACACAPSDPLAT | |
| SCHEMBL13746898 | 0.85 | HSD11B1 (0.39) | PSDPDE2A | |
| SCHEMBL13747128 | 0.85 | PLAT (0.34) | ACACBACACAPSDPLATPDE2A | |
| SCHEMBL4023129 | 0.85 | PDE2A (0.37) | TYMSPDE2A | |
| SCHEMBL4023133 | 0.85 | PDE2A (0.37) | TYMSPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100403-A1 | SUBSTITUTED ARYL PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |