Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25102231 | 0.82 | KDM4E (0.37) | KDM4EKMT2ACYP1A2CCR2FFAR3 | |
| SCHEMBL719286 | 0.78 | KDM4E (0.45) | KDM4EKMT2ACYP1A2SMN1; SMN2CCR2 | |
| SCHEMBL31057956 | 0.78 | KDM4E (0.41) | KDM4EKMT2ACYP1A2CCR2FFAR3 | |
| Hydrochloric Acid SCHEMBL17848601 | 0.77 | KDM4E (0.44) | KDM4EKMT2ACYP1A2SMN1; SMN2CCR2 | |
| SCHEMBL894742 | 0.75 | KDM4E (0.40) | KDM4EKMT2ACYP1A2FFAR3 | |
| SCHEMBL24025620 | 0.73 | KMT2A (0.38) | KDM4EKMT2ACYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL25229077 | 0.73 | ALDH1A1 (0.40) | KDM4EKMT2ACYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL25221272 | 0.73 | CYP1A2 (0.49) | KDM4EKMT2ACYP1A2ALDH1A1CCR2 | |
| SCHEMBL19262469 | 0.73 | SCN1A (0.37) | CYP1A2ALDH1A1SMN1; SMN2FFAR3CRBN | |
| SCHEMBL20224881 | 0.72 | EPHX1 (0.45) | KDM4EKMT2ACCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105348-A1 | IMIDAZOBENZAZEPINE CGRP RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2009-08-27 | — | — | WO | disclosed |