Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.45 |
| ▸ | PGR | P06401 | 10/20 | 0.45 |
| ▸ | AR | P10275 | 4/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4195609 | 1.00 | NR3C1 (0.45) | NR3C1PGRARNR3C2 | |
| SCHEMBL4195604 | 1.00 | NR3C1 (0.45) | NR3C1PGRARNR3C2 | |
| SCHEMBL4026187 | 0.81 | NR3C1 (0.40) | NR3C1PGRARNR3C2 | |
| SCHEMBL4193682 | 0.81 | NR3C1 (0.40) | NR3C1PGRARNR3C2 | |
| SCHEMBL4203237 | 0.80 | NR3C1 (0.39) | NR3C1PGRARNR3C2 | |
| SCHEMBL4203239 | 0.80 | NR3C1 (0.39) | NR3C1PGRARNR3C2 | |
| SCHEMBL4201052 | 0.80 | NR3C1 (0.39) | NR3C1PGRARNR3C2 | |
| SCHEMBL4201046 | 0.80 | NR3C1 (0.39) | NR3C1PGRARNR3C2 | |
| SCHEMBL4201047 | 0.80 | NR3C1 (0.39) | NR3C1PGRARNR3C2 | |
| SCHEMBL4199864 | 0.76 | NR3C1 (0.51) | NR3C1PGRARNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103007-A2 | STEROID HORMONE RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2009-08-20 | — | — | WO | disclosed |