Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | F2R | P25116 | 6/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CD69 | Q07108 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12187528 | 0.86 | F2R (0.44) | L3MBTL1GAAMAPTALDH1A1NPC1 | |
| SCHEMBL10204570 | 0.85 | F2R (0.41) | L3MBTL1GAAMAPTALDH1A1NPC1 | |
| SCHEMBL1188548 | 0.85 | F2R (0.44) | L3MBTL1GAAMAPTALDH1A1NPC1 | |
| SCHEMBL1189352 | 0.85 | L3MBTL1 (0.44) | L3MBTL1GAAMAPTALDH1A1NPC1 | |
| SCHEMBL1205744 | 0.84 | F2R (0.47) | L3MBTL1GAAMAPTALDH1A1NPC1 | |
| SCHEMBL1204388 | 0.84 | L3MBTL1 (0.46) | L3MBTL1GAAMAPTALDH1A1PLA2G2A | |
| SCHEMBL1205039 | 0.84 | F2R (0.46) | L3MBTL1GAAMAPTALDH1A1NPC1 | |
| SCHEMBL1190221 | 0.83 | CREBBP (0.47) | ALDH1A1SMN1; SMN2NR4A1NR4A2NR4A3 | |
| SCHEMBL1205102 | 0.82 | MAOB (0.39) | L3MBTL1GAAMAPTALDH1A1F2R | |
| SCHEMBL10204506 | 0.79 | MAOB (0.47) | GAANPC1POLBCASP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097970-A1 | TRIAZOLOPYRIDAZINES AS PAR1 INHIBITORS, PRODUCTION THEREOF, AND USE AS MEDICAMENTS | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |