Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14886253 | 0.77 | TSHR (0.33) | TSHR | |
| SCHEMBL8106091 | 0.75 | — | — | |
| SCHEMBL271740 | 0.74 | — | — | |
| SCHEMBL16080812 | 0.72 | — | — | |
| SCHEMBL14886363 | 0.72 | — | — | |
| SCHEMBL2390662 | 0.71 | TSHR (0.47) | ALDH1A1TSHR | |
| SCHEMBL28446602 | 0.71 | TSHR (0.47) | ALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL3498578 | 0.71 | TSHR (0.47) | ALDH1A1TSHR | |
| SCHEMBL28233227 | 0.71 | TSHR (0.47) | ALDH1A1TSHR | |
| Water SCHEMBL11633420 | 0.71 | TSHR (0.47) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7569579-B2 | for inhibition of HIV replication and treatment of acquired immune deficiency syndrome | SMITHKLINE BEECHAM CORPORATION (US) | 2009-08-04 | — | — | US | disclosed |