SCHEMBL1374774

SCHEMBL1374774

CCSCn1c(=O)c(C(=O)OC)cc2cccnc21

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 16/20 0.47
CNR1 P21554 11/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1372532 0.87 CNR2 (0.47) CNR2CNR1
SCHEMBL1376584 0.86 CNR2 (0.46) CNR2CNR1
Hydrochloric Acid SCHEMBL1376586 0.86 CNR2 (0.46) CNR2CNR1
SCHEMBL1372692 0.84 CNR2 (0.47) CNR2CNR1
SCHEMBL1373864 0.84 CNR2 (0.42) CNR2CNR1
SCHEMBL1375898 0.79 AHR (0.61) CNR2CNR1
SCHEMBL1372393 0.77 CNR2 (0.44) CNR2CNR1
SCHEMBL16250044 0.75 CNR2 (0.46) CNR2CNR1
SCHEMBL15334959 0.74 CNR2 (0.49) CNR2CNR1
SCHEMBL18976549 0.74 MTNR1A (0.46) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2394995-B1 RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES KUMIAI CHEMICAL INDUSTRY CO (JP) 2014-01-15 EP disclosed
US-8334236-B2 Ring-fused 2-pyridone derivatives and herbicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2012-12-18 US disclosed
US-20110287937-A1 RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2011-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110287937-A1 RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES CBR3, CBR1, CHRM1 CNR2 516/4885CNR1 327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.