Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.48 |
| ▸ | PGR | P06401 | 5/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748628 | 1.00 | AR (0.48) | ARPGRNR3C1NR3C2CXCR1 | |
| SCHEMBL15712940 | 0.87 | AR (0.39) | ARPGRNR3C1CXCR1CXCR2 | |
| SCHEMBL1291460 | 0.86 | AR (0.51) | ARPGRNR3C1NR3C2 | |
| SCHEMBL1364405 | 0.86 | AR (0.51) | ARPGRNR3C1NR3C2 | |
| SCHEMBL12342663 | 0.86 | AR (0.51) | ARPGRNR3C1NR3C2 | |
| SCHEMBL1362970 | 0.86 | AR (0.51) | ARPGRNR3C1NR3C2 | |
| SCHEMBL12342293 | 0.86 | AR (0.51) | ARPGRNR3C1NR3C2 | |
| SCHEMBL12140365 | 0.86 | AR (0.51) | ARPGRNR3C1NR3C2 | |
| SCHEMBL1364620 | 0.86 | AR (0.47) | ARPGRNR3C1NR3C2CXCR1 | |
| SCHEMBL2386549 | 0.86 | AR (0.47) | ARPGRNR3C1NR3C2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260028-B1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH INC (US) | 2014-05-07 | — | — | EP | disclosed |
| WO-2009105214-A2 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH, INC. (US) | 2009-08-27 | — | — | WO | disclosed |