Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.39 |
| ▸ | PGR | P06401 | 3/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15713024 | 0.90 | CXCR1 (0.37) | ARPGRCXCR1CXCR2L3MBTL1 | |
| SCHEMBL15712938 | 0.90 | CXCR1 (0.37) | ARPGRCXCR1CXCR2L3MBTL1 | |
| SCHEMBL13747780 | 0.87 | AR (0.48) | ARPGRCXCR1CXCR2L3MBTL1 | |
| SCHEMBL13748628 | 0.87 | AR (0.48) | ARPGRCXCR1CXCR2L3MBTL1 | |
| SCHEMBL15712968 | 0.86 | AR (0.40) | ARPGRCXCR1CXCR2L3MBTL1 | |
| SCHEMBL15712958 | 0.78 | CXCR1 (0.36) | ARPGRCXCR1CXCR2L3MBTL1 | |
| SCHEMBL15713138 | 0.77 | CXCR1 (0.34) | ARPGRCXCR1CXCR2L3MBTL1 | |
| SCHEMBL15712932 | 0.76 | KAT6A (0.38) | ALDH1A1 | |
| SCHEMBL1364415 | 0.75 | AR (0.40) | ARPGRCXCR1CXCR2L3MBTL1 | |
| SCHEMBL12140371 | 0.73 | S1PR3 (0.39) | L3MBTL1KDM4EALDH1A1GAAS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260028-B1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH INC (US) | 2014-05-07 | — | — | EP | disclosed |