Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.37 |
| ▸ | PGR | P06401 | 5/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1363933 | 0.84 | AR (0.45) | ARPGRNR3C2NR3C1ALDH1A1 | |
| SCHEMBL1363936 | 0.84 | AR (0.45) | ARPGRNR3C2NR3C1ALDH1A1 | |
| SCHEMBL1364779 | 0.83 | ALDH1A1 (0.39) | ARPGRSMN1; SMN2CXCR1CXCR2 | |
| SCHEMBL1363767 | 0.83 | AR (0.43) | ARPGRNR3C2NR3C1CXCR1 | |
| SCHEMBL1364665 | 0.83 | AR (0.43) | ARPGRNR3C2NR3C1CXCR1 | |
| SCHEMBL1364781 | 0.83 | ALDH1A1 (0.39) | ARPGRSMN1; SMN2CXCR1CXCR2 | |
| SCHEMBL12140389 | 0.83 | AR (0.43) | ARPGRNR3C2NR3C1ALDH1A1 | |
| SCHEMBL1365443 | 0.78 | AR (0.42) | ARPGRALDH1A1 | |
| SCHEMBL1365014 | 0.78 | AR (0.42) | ARPGRALDH1A1 | |
| SCHEMBL15712960 | 0.78 | AR (0.38) | ARPGRNR3C2NR3C1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105214-A2 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH, INC. (US) | 2009-08-27 | — | — | WO | disclosed |