Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | VEGFA | P15692 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13747641 | 0.98 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMPOCHRNA7 | |
| SCHEMBL755778 | 0.84 | KMT2A (0.55) | ALDH1A1MEN1KMT2AMPOCHRNA7 | |
| SCHEMBL753109 | 0.83 | KMT2A (0.57) | ALDH1A1MEN1KMT2AMPOCHRNA7 | |
| SCHEMBL19364613 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AMPOCHRNA7 | |
| SCHEMBL890075 | 0.83 | MEN1 (0.54) | ALDH1A1MEN1KMT2AMPOCHRNA7 | |
| SCHEMBL890107 | 0.81 | KMT2A (0.56) | ALDH1A1MEN1KMT2AMPOCHRNA7 | |
| SCHEMBL19364663 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AMPOCHRNA7 | |
| SCHEMBL11196594 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AMPOCHRNA7 | |
| SCHEMBL10140834 | 0.80 | KMT2A (0.51) | ALDH1A1MEN1KMT2AMPOCHRNA7 | |
| SCHEMBL888667 | 0.80 | MEN1 (0.51) | ALDH1A1MEN1KMT2AMPOCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102325-A1 | IMIDAZOLYL BIPHENYL IMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-20 | — | — | WO | disclosed |
| WO-2008021927-A2 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-21 | — | — | WO | disclosed |