SCHEMBL13748419

SCHEMBL13748419

N#Cc1ccc(N(c2ccccc2)c2ccc(N(c3ccccc3)c3ccc(N(c4ccccc4)c4ccc(N(c5ccccc5)c5ccc(N(c6ccccc6)c6ccc(N(c7ccccc7)c7ccc(N(c8ccccc8)c8ccc(C#N)cc8)cc7)cc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.59
MAOB P27338 4/20 0.50
ALDH1A1 P00352 3/20 0.50
MAOA P21397 3/20 0.50
MAPT P10636 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
KDM4E B2RXH2 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CRHBP P24387 2/20 0.47
CRHR2 Q13324 2/20 0.47
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
NPC1 O15118 1/20 0.45
CYP2A6 P11509 2/20 0.43
ENPP2 Q13822 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13748820 1.00 TSHR (0.59) TSHRMAOBALDH1A1MAOAMAPT
SCHEMBL151680 1.00 TSHR (0.59) TSHRMAOBALDH1A1MAOAMAPT
SCHEMBL13748038 1.00 TSHR (0.59) TSHRMAOBALDH1A1MAOAMAPT
SCHEMBL8849586 1.00 TSHR (0.59) TSHRMAOBALDH1A1MAOAMAPT
SCHEMBL15807473 0.94 TSHR (0.52) TSHRMAOBALDH1A1MAOAMAPT
SCHEMBL15807463 0.94 TSHR (0.52) TSHRMAOBALDH1A1MAOAMAPT
SCHEMBL20855355 0.94 TSHR (0.52) TSHRMAOBALDH1A1MAOAMAPT
SCHEMBL16484549 0.94 TSHR (0.52) TSHRMAOBALDH1A1MAOAMAPT
SCHEMBL16484551 0.94 TSHR (0.52) TSHRMAOBALDH1A1MAOAMAPT
SCHEMBL995812 0.90 CA2 (0.50) TSHRMAOBALDH1A1MAOAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7576484-B2 Organic electroluminescence device LG DISPLAY CO., LTD. (KR) 2009-08-18 US disclosed