SCHEMBL13748604

SCHEMBL13748604

OC(CNc1cc(-c2ccc(I)c(I)c2)ncn1)c1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3427766 0.88 FAAH (0.78) FAAH
SCHEMBL13663337 0.88 FAAH (0.78) FAAH
SCHEMBL3431292 0.86 FAAH (0.83) FAAH
SCHEMBL13748619 0.86 FAAH (0.75) FAAH
SCHEMBL3405941 0.85 FAAH (1.00) FAAH
SCHEMBL3401403 0.85 FAAH (1.00) FAAH
SCHEMBL4292041 0.84 FAAH (0.74) FAAH
SCHEMBL4291985 0.84 FAAH (1.00) FAAH
SCHEMBL4298948 0.84 FAAH (0.80) FAAH
SCHEMBL3405945 0.83 FAAH (0.78) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009105220-A1 ARYL-HYDROXYETHYLAMINO-PYRIMIDINES AND TRIAZINES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE JANSSEN PHARMACEUTICA N.V. (BE) 2009-08-27 WO disclosed