Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 11/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1747409 | 0.96 | PRCP (0.69) | PRCPKCNH2CYP3A4CYP2C9NR1I2 | |
| SCHEMBL13747759 | 0.92 | PRCP (0.69) | PRCPKCNH2CYP3A4CYP2C9NR1I2 | |
| SCHEMBL10039628 | 0.90 | PRCP (0.62) | PRCPKCNH2CYP3A4CYP2C9NR1I2 | |
| SCHEMBL12565050 | 0.88 | PRCP (0.63) | PRCPKCNH2CYP3A4CYP2C9CYP1A2 | |
| SCHEMBL13747964 | 0.88 | PRCP (0.61) | PRCPKCNH2CYP3A4CYP2C9NR1I2 | |
| SCHEMBL13747250 | 0.88 | PRCP (0.60) | PRCPKCNH2CYP3A4CYP2C9NR1I2 | |
| SCHEMBL12160080 | 0.88 | PRCP (0.60) | PRCPKCNH2CYP3A4CYP2C9NR1I2 | |
| SCHEMBL13747178 | 0.87 | PRCP (0.60) | PRCPKCNH2CYP3A4CYP2C9NR1I2 | |
| SCHEMBL13748255 | 0.87 | PRCP (0.59) | PRCPKCNH2CYP3A4CYP2C9NR1I2 | |
| SCHEMBL13747125 | 0.87 | PRCP (0.64) | PRCPKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102325-A1 | IMIDAZOLYL BIPHENYL IMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-20 | — | — | WO | disclosed |
| WO-2008021927-A2 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-21 | — | — | WO | disclosed |