Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 9/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748980 | 0.99 | SLC6A9 (0.41) | SLC6A9KCNH2KDM5BSMN1; SMN2KMT2A | |
| SCHEMBL13749042 | 0.96 | SLC6A9 (0.41) | SLC6A9KCNH2KDM5BKMT2AALDH1A1 | |
| SCHEMBL13748936 | 0.96 | SLC6A9 (0.40) | SLC6A9KCNH2KDM5BKMT2A | |
| SCHEMBL13749340 | 0.92 | SLC6A9 (0.39) | SLC6A9KCNH2KDM5BKMT2AMAPT | |
| SCHEMBL13748067 | 0.91 | SLC6A9 (0.40) | SLC6A9KCNH2SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL13749140 | 0.91 | SLC6A9 (0.41) | SLC6A9KCNH2KMT2AALDH1A1MAPT | |
| SCHEMBL13749100 | 0.91 | SLC6A9 (0.42) | SLC6A9KCNH2KMT2AALDH1A1PDK2 | |
| SCHEMBL13748784 | 0.89 | SLC6A9 (0.39) | SLC6A9KCNH2KMT2AALDH1A1PDK2 | |
| SCHEMBL13748799 | 0.89 | SLC6A9 (0.39) | SLC6A9KCNH2PDK2 | |
| SCHEMBL13749141 | 0.88 | SLC6A9 (0.43) | SLC6A9KCNH2KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100120-A2 | PYRIDINYL-SUBSTITUTED PIPERAZINYL OXOETHYL TETRAHYDROPYRAZOLOPYRIDINES | NEUROGEN CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |