Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 16/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105843 | 0.93 | CASR (0.45) | CASRCYP2D6 | |
| Hydrochloric Acid SCHEMBL1096054 | 0.92 | CASR (0.46) | CASRCYP2D6 | |
| SCHEMBL1096436 | 0.87 | CASR (0.42) | CASRCYP2D6 | |
| SCHEMBL1105823 | 0.87 | CASR (0.46) | CASRCYP2D6 | |
| Hydrochloric Acid SCHEMBL1096881 | 0.86 | CASR (0.43) | CASRCYP2D6 | |
| SCHEMBL4105924 | 0.86 | CASR (0.46) | CASRCYP2D6 | |
| SCHEMBL4105928 | 0.86 | CASR (0.46) | CASRCYP2D6 | |
| SCHEMBL1096871 | 0.85 | UBE2M (0.43) | CASR | |
| SCHEMBL13748648 | 0.85 | CASR (0.48) | CASRCYP2D6 | |
| SCHEMBL1105744 | 0.83 | CASR (0.42) | CASRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085383-A1 | PIPERIDINE DERIVATIVES OR SALTS THEREOF | Astellas Pharma Inc. (JP) | 2009-08-05 | — | — | EP | disclosed |