Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15591989 | 1.00 | CHRM2 (0.48) | CHRM2LCKCA12CA1CA2 | |
| SCHEMBL3320230 | 0.97 | LCK (0.46) | CHRM2LCKCA12CA1CA2 | |
| SCHEMBL2609752 | 0.97 | LCK (0.46) | CHRM2LCKCA12CA1CA2 | |
| SCHEMBL15591978 | 0.97 | CHRM2 (0.50) | CHRM2LCKCA12CA1CA2 | |
| SCHEMBL711967 | 0.97 | CHRM2 (0.50) | CHRM2LCKCA12CA1CA2 | |
| SCHEMBL2055292 | 0.97 | LCK (0.46) | CHRM2LCKCA12CA1CA2 | |
| SCHEMBL2402964 | 0.97 | CHRM2 (0.50) | CHRM2LCKCA12CA1CA2 | |
| SCHEMBL15591996 | 0.97 | CHRM2 (0.50) | CHRM2LCKCA12CA1CA2 | |
| SCHEMBL13748874 | 0.97 | CHRM2 (0.50) | CHRM2LCKCA12CA1CA2 | |
| SCHEMBL715461 | 0.97 | CHRM2 (0.50) | CHRM2LCKCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097127-A1 | PHARMACEUTICAL COMPOSITIONS | GENZYME CORPORATION (US) | 2009-08-06 | — | — | WO | disclosed |