Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3320230 | 1.00 | LCK (0.46) | LCKCHRM2NFKB1CA12CA1 | |
| SCHEMBL3319406 | 1.00 | LCK (0.46) | LCKCHRM2NFKB1CA12CA1 | |
| SCHEMBL2055292 | 1.00 | LCK (0.46) | LCKCHRM2NFKB1CA12CA1 | |
| SCHEMBL15790833 | 1.00 | LCK (0.46) | LCKCHRM2NFKB1CA12CA1 | |
| SCHEMBL17123444 | 1.00 | LCK (0.46) | LCKCHRM2NFKB1CA12CA1 | |
| SCHEMBL13748877 | 0.97 | CHRM2 (0.48) | LCKCHRM2NFKB1CA12CA1 | |
| SCHEMBL15591989 | 0.97 | CHRM2 (0.48) | LCKCHRM2NFKB1CA12CA1 | |
| SCHEMBL10051135 | 0.96 | LCK (0.48) | LCKCHRM2NFKB1CA12CA1 | |
| SCHEMBL13913105 | 0.96 | LCK (0.48) | LCKCHRM2NFKB1CA12CA1 | |
| SCHEMBL13748668 | 0.96 | LCK (0.48) | LCKCHRM2NFKB1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150011645-A1 | AMINE DENDRIMERS | GENZYME CORP (US) | 2015-01-08 | — | — | US | claimed |
| US-20100124542-A1 | AMINE DENDRIMERS | GENZYME CORPORATION (US) | 2010-05-20 | — | — | US | claimed |
| US-11834546-B2 | Polyurethane-based composition | BOSTIK SA (FR) | 2023-12-05 | — | — | US | disclosed |
| US-11834546-B2 | Polyurethane-based composition | BOSTIK SA (FR) | 2023-12-05 | — | — | US | disclosed |
| US-20220033563-A1 | POLYURETHANE-BASED COMPOSITION | BOSTIK SA (FR) | 2022-02-03 | — | — | US | disclosed |
| US-20200385509-A1 | POLYURETHANE-BASED COMPOSITION | BOSTIK SA (FR) | 2020-12-10 | — | — | US | disclosed |
| US-10696879-B2 | Adhesive dual-component composition based on polyurethane | BOSTIK SA (FR) | 2020-06-30 | — | — | US | disclosed |
| US-20200157415-A1 | PROPPANT TREATMENT AND ENHANCED WATER IMBIBITION IN TIGHT SUBTERRANEAN FORMATIONS BY USING DENDRIMERS | TRICAN WELL SERVICE LTD. (CA) | 2020-05-21 | — | — | US | disclosed |
| US-20190241779-A1 | ADHESIVE DUAL-COMPONENT COMPOSITION BASED ON POLYURETHANE | BOSTIK SA (FR) | 2019-08-08 | — | — | US | disclosed |
| US-9764068-B2 | Immobilised biological entities | W.L. GORE AND ASSOCIATES INC. (US) | 2017-09-19 | — | — | US | disclosed |
| US-20160310646-A1 | IMMOBILISED BIOLOGICAL ENTITIES | W. L. GORE & ASSOCIATES, INC. | 2016-10-27 | — | — | US | disclosed |
| US-8114393-B2 | Methods and compositions for phosphate binding | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-02-14 | — | — | US | disclosed |
| US-20110021626-A1 | ENCAPSULATION OF VITAMIN C INTO WATER SOLUBLE DENDRIMERS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2011-01-27 | — | — | US | disclosed |
| US-20110021626-A1 | ENCAPSULATION OF VITAMIN C INTO WATER SOLUBLE DENDRIMERS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) | 2011-01-27 | — | — | US | disclosed |
| US-20100124542-A1 | AMINE DENDRIMERS | GENZYME CORPORATION (US) | 2010-05-20 | — | — | US | disclosed |
| WO-2009112682-A1 | ENCAPSULATION OF VITAMIN C INTO WATER SOLUBLE DENDRIMERS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS (FR) | 2009-09-17 | — | — | WO | disclosed |
| US-20090004133-A1 | Methods and compositions for phosphate binding | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2009-01-01 | — | — | US | disclosed |
| US-20090004133-A1 | Methods and compositions for phosphate binding | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2009-01-01 | — | — | US | disclosed |
| US-20080267903-A1 | Cationic polyamines and dendrimeric polymers; anti-proliferative agents; for treatment of neoplasms and tumours, inflammatory disorders, autoimmune disorders, psoriasis, and atherosclerosis; gene therapy | UNIVERSITY COLLEGE LONDON (GB) | 2008-10-30 | — | — | US | disclosed |
| US-20080267903-A1 | Cationic polyamines and dendrimeric polymers; anti-proliferative agents; for treatment of neoplasms and tumours, inflammatory disorders, autoimmune disorders, psoriasis, and atherosclerosis; gene therapy | UNIVERSITY COLLEGE LONDON (GB) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100124542-A1 | AMINE DENDRIMERS | PHOSPHO1, PHPT1, PPIP5K2 | LCK 2840/4885CHRM2 1071/4885NFKB1 3316/4885 |
| US-20090004133-A1 | Methods and compositions for phosphate binding | SI, SLC10A2, SLC34A3 | LCK 2134/4885CHRM2 1804/4885NFKB1 1704/4885 |
| US-20110021626-A1 | ENCAPSULATION OF VITAMIN C INTO WATER SOLUBLE DENDRIMERS | PROC, CD44, CCNC | LCK 4765/4885CHRM2 1073/4885NFKB1 2669/4885 |
| US-20080267903-A1 | Cationic polyamines and dendrimeric polymers; anti-proliferative agents; for treatment of neoplasms and tumours, inflammatory disorders, autoimmune disorders, psoriasis, and atherosclerosis; gene therapy | PCNA, SSB, PKD1 | LCK 1174/4885CHRM2 4774/4885NFKB1 694/4885 |
| US-20150011645-A1 | AMINE DENDRIMERS | PHOSPHO1, PHPT1, PPIP5K2 | LCK 2840/4885CHRM2 1071/4885NFKB1 3316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.