SCHEMBL13748901

SCHEMBL13748901

CC(F)(c1cccc(-c2cc(NC[C@H](O)c3ccccc3)ncn2)c1)C(F)(F)F

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4296742 0.90 FAAH (0.84) FAAH
SCHEMBL4294661 0.89 FAAH (1.00) FAAH
SCHEMBL13663602 0.89 FAAH (1.00) FAAH
SCHEMBL4298997 0.83 FAAH (0.83) FAAH
SCHEMBL4295390 0.82 FAAH (0.81) FAAH
SCHEMBL3431292 0.82 FAAH (0.83) FAAH
SCHEMBL4294760 0.82 FAAH (1.00) FAAH
SCHEMBL4297931 0.81 FAAH (0.83) FAAH
SCHEMBL4297022 0.81 FAAH (1.00) FAAH
SCHEMBL4303442 0.81 FAAH (1.00) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009105220-A1 ARYL-HYDROXYETHYLAMINO-PYRIMIDINES AND TRIAZINES AS MODULATORS OF FATTY ACID AMIDE HYDROLASE JANSSEN PHARMACEUTICA N.V. (BE) 2009-08-27 WO disclosed