Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1178873 | 0.82 | ALDH1A1 (0.35) | KMT2AALOX12MEN1ALDH1A1TSHR | |
| SCHEMBL13749022 | 0.82 | ALDH1A1 (0.31) | KMT2AALOX12MEN1ALDH1A1TSHR | |
| SCHEMBL8570905 | 0.80 | CYP2C9 (0.44) | KMT2AALOX12MEN1ALDH1A1TSHR | |
| SCHEMBL8570901 | 0.80 | CYP2C9 (0.44) | KMT2AALOX12MEN1ALDH1A1TSHR | |
| SCHEMBL11786885 | 0.80 | CYP2C9 (0.44) | KMT2AALOX12MEN1ALDH1A1TSHR | |
| Acetic Acid SCHEMBL29570469 | 0.78 | ALDH1A1 (0.33) | KMT2AALOX12MEN1ALDH1A1TSHR | |
| SCHEMBL10920226 | 0.78 | KMT2A (0.37) | KMT2AALOX12MEN1ALDH1A1TSHR | |
| SCHEMBL10920229 | 0.78 | KMT2A (0.37) | KMT2AALOX12MEN1ALDH1A1TSHR | |
| SCHEMBL30517388 | 0.77 | ALDH1A1 (0.32) | KMT2AALOX12MEN1ALDH1A1TSHR | |
| SCHEMBL13415889 | 0.77 | ALDH1A1 (0.32) | KMT2AALOX12MEN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737876-B1 | AVERMECTIN AND AVERMECTIN MONOSACCHARIDE SUBSTITUTED IN THE 4\"-AND 4'-POSITION RESPECTIVELY | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-05 | — | — | EP | disclosed |