Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL1374897

C=CC(=O)O.OCCOCC(O)Oc1ccccc1.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO.OCCOCCO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
ALDH1A1 P00352 4/20 0.39
RECQL P46063 1/20 0.39
KDM4E B2RXH2 4/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GAA P10253 1/20 0.35
PPARG P37231 5/20 0.34
PPARA Q07869 5/20 0.34
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
TGM2 P21980 1/20 0.33
TEAD1 P28347 1/20 0.33
TEAD3 Q99594 1/20 0.33
LMNA P02545 1/20 0.33
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
AKT1 P31749 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL1378128 1.00 THRB (0.40) THRBALDH1A1RECQLKDM4EKMT2A
Acrylic Acid SCHEMBL1523938 0.99 THRB (0.39) THRBALDH1A1RECQLKDM4EKMT2A
Acrylic Acid SCHEMBL125490 0.99 THRB (0.39) THRBALDH1A1RECQLKDM4EKMT2A
Acrylic Acid SCHEMBL1524153 0.99 THRB (0.39) THRBALDH1A1RECQLKDM4EKMT2A
Acrylic Acid SCHEMBL183165 0.99 THRB (0.39) THRBALDH1A1RECQLKDM4EKMT2A
Acrylic Acid SCHEMBL9577871 0.99 THRB (0.39) THRBALDH1A1RECQLKDM4EKMT2A
Acrylic Acid SCHEMBL1524949 0.99 THRB (0.39) THRBALDH1A1RECQLKDM4EKMT2A
Acrylic Acid SCHEMBL1524075 0.99 THRB (0.39) THRBALDH1A1RECQLKDM4EKMT2A
Acrylic Acid SCHEMBL1523730 0.99 THRB (0.39) THRBALDH1A1RECQLKDM4EKMT2A
Acrylic Acid SCHEMBL181510 0.99 THRB (0.41) THRBALDH1A1RECQLKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2390724-B1 Toner, image forming apparatus, image forming method and process cartridge RICOH CO LTD (JP) 2015-08-26 EP disclosed
US-8614040-B2 Electrostatic image developing toner, toner container and process cartridge RICOH COMPANY, LTD. (JP) 2013-12-24 US disclosed
US-8518625-B2 Toner, image forming apparatus, image forming method and process cartridge RICOH COMPANY, LTD. (JP) 2013-08-27 US disclosed
US-20120237253-A1 ELECTROSTATIC IMAGE DEVELOPING TONER, TONER CONTAINER AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2012-09-20 US disclosed
EP-2390724-A1 Toner, image forming apparatus, image forming method and process cartridge Ricoh Company, Ltd. (JP) 2011-11-30 EP disclosed
US-20110287356-A1 TONER, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2011-11-24 US disclosed