Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.41 |
| ▸ | CASR | P41180 | 11/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105887 | 0.92 | CYP2D6 (0.43) | CYP2D6CASRMETAP2METAP1 | |
| SCHEMBL1106014 | 0.86 | CYP2D6 (0.43) | CYP2D6CASRMETAP2METAP1 | |
| SCHEMBL13748850 | 0.85 | CASR (0.40) | CYP2D6CASRCCR5 | |
| SCHEMBL1106023 | 0.83 | CASR (0.44) | CYP2D6CASR | |
| SCHEMBL1105867 | 0.83 | CASR (0.47) | CYP2D6CASR | |
| SCHEMBL13748632 | 0.83 | CASR (0.42) | CYP2D6CASRCCR5 | |
| SCHEMBL1106019 | 0.81 | CASR (0.46) | CYP2D6CASR | |
| SCHEMBL1106028 | 0.80 | CASR (0.47) | CYP2D6CASR | |
| SCHEMBL1105891 | 0.80 | CASR (0.44) | CYP2D6CASR | |
| SCHEMBL1105859 | 0.80 | CASR (0.44) | CYP2D6CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085383-A1 | PIPERIDINE DERIVATIVES OR SALTS THEREOF | Astellas Pharma Inc. (JP) | 2009-08-05 | — | — | EP | disclosed |