Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ALB | P02768 | 1/20 | 0.63 |
| ▸ | PI4KA | P42356 | 3/20 | 0.57 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.57 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.57 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197787 | 1.00 | ADA (0.65) | ADAMAPK1ALDH1A1LMNAALB | |
| SCHEMBL18572374 | 1.00 | ADA (0.65) | ADAMAPK1ALDH1A1LMNAALB | |
| SCHEMBL3541 | 1.00 | ADA (0.65) | ADAMAPK1ALDH1A1LMNAALB | |
| SCHEMBL29609293 | 1.00 | ADA (0.65) | ADAMAPK1ALDH1A1LMNAALB | |
| SCHEMBL10381269 | 1.00 | ADA (0.65) | ADAMAPK1ALDH1A1LMNAALB | |
| SCHEMBL8094890 | 1.00 | ADA (0.65) | ADAMAPK1ALDH1A1LMNAALB | |
| SCHEMBL20419221 | 1.00 | ADA (0.65) | ADAMAPK1ALDH1A1LMNAALB | |
| Phosphoric Acid SCHEMBL8630949 | 0.94 | MAPK1 (0.60) | ADAMAPK1ALDH1A1LMNAALB | |
| Phosphoric Acid SCHEMBL4966781 | 0.94 | MAPK1 (0.60) | ADAMAPK1ALDH1A1LMNAALB | |
| Phosphoric Acid SCHEMBL79814 | 0.94 | MAPK1 (0.60) | ADAMAPK1ALDH1A1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011774-A | Dideoxyinosine by enzymatic deamination of dideoxyadenosine | BRISTOL-MYERS SQUIBB CO. (US) | 1991-04-30 | — | — | US | claimed |
| EP-4032897-B1 | MODIFIED FLUORINATED NUCLEOSIDE ANALOGUES | GILEAD PHARMASSET LLC (US) | 2025-01-29 | — | — | EP | disclosed |
| EP-2604620-B9 | Modified fluorinated nucleoside analogues | GILEAD PHARMASSET LLC (US) | 2024-10-23 | — | — | EP | disclosed |
| EP-2604620-B2 | Modified fluorinated nucleoside analogues | GILEAD PHARMASSET LLC (US) | 2024-06-19 | — | — | EP | disclosed |
| EP-4032897-A1 | MODIFIED FLUORINATED NUCLEOSIDE ANALOGUES | Gilead Pharmasset LLC (US) | 2022-07-27 | — | — | EP | disclosed |
| EP-2120566-B1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS | IDENIX PHARMACEUTICALS LLC (US) | 2019-05-08 | — | — | EP | disclosed |
| EP-2120566-B1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS | IDENIX PHARMACEUTICALS LLC (US) | 2019-05-08 | — | — | EP | disclosed |
| US-9249173-B2 | Compounds and pharmaceutical compositions for the treatment of viral infections | IDENIX PHARMACEUTICALS, LLC (US) | 2016-02-02 | — | — | US | disclosed |
| US-9249173-B2 | Compounds and pharmaceutical compositions for the treatment of viral infections | IDENIX PHARMACEUTICALS, LLC (US) | 2016-02-02 | — | — | US | disclosed |
| US-9249173-B2 | Compounds and pharmaceutical compositions for the treatment of viral infections | IDENIX PHARMACEUTICALS, LLC (US) | 2016-02-02 | — | — | US | disclosed |
| US-20040175804-A1 | Process for preparing dideoxyinosine using adenosine deaminase enzyme | BRISTOL-MYERS SQUIBB COMPANY | 2004-09-09 | — | — | US | disclosed |
| EP-0707481-B1 | L-2',3'-DIDEOXY NUCLEOSIDE ANALOGS AS ANTI-HEPATITIS B (HBV) AND ANTI-HIV AGENTS | UNIV YALE (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5830881-A | L-2'3',dideoxy nucleoside analogs as anti-hepatitus B (HBV) agents | YALE UNIVERSITY (US) | 1998-11-03 | — | — | US | disclosed |
| US-5631239-A | VIRICIDES FOR HEPATITIS | YALE UNIVERSITY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5627160-A | L-2',3'-dideoxy nucleoside analogs as anti-hepatitis B (HBV) and anti-HIV agents | YALE UNIVERSITY (US) | 1997-05-06 | — | — | US | disclosed |
| US-5561120-A | LOW TOXICITY TO HOST CELLS | YALE UNIVERSITY (US) | 1996-10-01 | — | — | US | disclosed |
| EP-0707481-A4 | — | — | 1996-05-29 | — | — | EP | disclosed |
| EP-0707481-A1 | L-2',3'-DIDEOXY NUCLEOSIDE ANALOGS AS ANTI-HEPATITIS B (HBV) AND ANTI-HIV AGENTS | YALE UNIVERSITY (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1994027616-A1 | L-2',3'-DIDEOXY NUCLEOSIDE ANALOGS AS ANTI-HEPATITIS B (HBV) AND ANTI-HIV AGENTS | YALE UNIVERSITY (US) | 1994-12-08 | — | — | WO | disclosed |
| US-5011774-A | Dideoxyinosine by enzymatic deamination of dideoxyadenosine | BRISTOL-MYERS SQUIBB CO. (US) | 1991-04-30 | — | — | US | disclosed |