Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ALB | P02768 | 1/20 | 0.60 |
| ▸ | ADA | P00813 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | PI4KA | P42356 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.52 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL79814 | 1.00 | MAPK1 (0.60) | MAPK1ALDH1A1LMNAALBADA | |
| Phosphoric Acid SCHEMBL4966781 | 1.00 | MAPK1 (0.60) | MAPK1ALDH1A1LMNAALBADA | |
| SCHEMBL6915651 | 0.96 | MAPK1 (0.58) | MAPK1ALDH1A1LMNAALBADA | |
| SCHEMBL8094890 | 0.94 | ADA (0.65) | MAPK1ALDH1A1LMNAALBADA | |
| SCHEMBL10381269 | 0.94 | ADA (0.65) | MAPK1ALDH1A1LMNAALBADA | |
| SCHEMBL9197787 | 0.94 | ADA (0.65) | MAPK1ALDH1A1LMNAALBADA | |
| SCHEMBL1374909 | 0.94 | ADA (0.65) | MAPK1ALDH1A1LMNAALBADA | |
| SCHEMBL29609293 | 0.94 | ADA (0.65) | MAPK1ALDH1A1LMNAALBADA | |
| SCHEMBL3541 | 0.94 | ADA (0.65) | MAPK1ALDH1A1LMNAALBADA | |
| SCHEMBL20419221 | 0.94 | ADA (0.65) | MAPK1ALDH1A1LMNAALBADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566140-B1 | Method for producing dinucleoside polyphosphate, nucleoside polyphosphate or derivatives thereof | UNITIKA LTD (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5306629-A | Two-stage reaction using two enzymes: adenosine-5-triphosphate sulfurylase and diadenosine tetraphosphate phosphorylase as catalysts, and adenosine-5-triphosphate, polyphosphate and a sulfate as substrates | UNITIKA LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0566140-A2 | Method for producing dinucleoside polyphosphate, nucleoside polyphosphate or derivatives thereof | UNITIKA LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |
| EP-0247819-B1 | PROCESS FOR PRODUCING DIADENOSINE TETRAPHOSPHATE AND DERIVATIVES THEREOF | UNITIKA LTD. (JP) | 1991-07-24 | — | — | EP | disclosed |
| US-4886749-A | Process for producing diadenosine tetraphosphate and derivatives thereof | UNITIKA LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0247819-A2 | Process for producing diadenosine tetraphosphate and derivatives thereof | UNITIKA LTD. (JP) | 1987-12-02 | — | — | EP | disclosed |